piRNA clusters and open chromatin structure
نویسندگان
چکیده
منابع مشابه
Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.
Small noncoding RNAs that associate with Piwi proteins, called piRNAs, serve as guides for repression of diverse transposable elements in germ cells of metazoa. In Drosophila, the genomic regions that give rise to piRNAs, the so-called piRNA clusters, are transcribed to generate long precursor molecules that are processed into mature piRNAs. How genomic regions that give rise to piRNA precursor...
متن کاملMisprocessed tRNA response targets piRNA clusters.
Germline PIWI-interacting RNA (piRNA) clusters have a characteristic transcriptional status; although they do not have their own promoters, both genomic strands are transcribed, while splicing and 30 processing signals are neglected. How this transcription is maintained remains unknown. Molla-Herman et al (2015) discovered that mutations in a tRNA processing factor cause the loss of transcripti...
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PIWI-interacting RNA (piRNA) clusters act as anti-transposon/retrovirus centers. Integration of selfish jumping elements into piRNA clusters generates de novo piRNAs, which in turn exert trans-silencing activity against these elements in animal gonads. To date, neither genome-wide chromatin modification states of piRNA clusters nor a mode for piRNA precursor transcription have been well underst...
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piRNAs (PIWI-interacting RNAs), which are generally 24–32 nucleotides in length, are defined by their specific association to the PIWI subfamily of AGO/ PIWI family proteins. piRNAs are mainly made in animal gonads, and are essential to silence transposons during germline development [1]. In Drosophila, the genomic regions that transcribe piRNA precursors are named as piRNA clusters. The primar...
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DFT and QTAIM computations have been performed on numbers of pure nitrogen cluster speciesi.e. Nn (n = 4, 6) for investigating the structure and bonding. This study is critical since thesemolecules have been nominated as the good synthetic targets of High Energy Materials (HEM).0nthe other hand the decomposition mechanism is closely depends on the bonding pattern. Thislatter concept was searche...
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ژورنال
عنوان ژورنال: Mobile DNA
سال: 2014
ISSN: 1759-8753
DOI: 10.1186/1759-8753-5-22